Antimicrobial Activity of Silver Nanoparticles against Clinical Biofilms from Patients with and without Dental Caries

Dental caries is an infectious oral disease originated by the presence of different microorganisms from well-defined biofilms. Many treatments for dental have been demonstrated to be successful protocols; however, incidence and prevalence remain still high. Although silver nanoparticles (AgNPs) shown excellent antimicrobial properties, even against bacteria, there no available scientific information that has evaluated activity AgNPs biofilms subjects with active caries. The objective this research was evaluate inhibitory effect in without Two sizes were prepared characterized. plaque samples collected 30 Microbiological analysis determined minimum concentration (MIC) nanoparticles, distribution microbial strains identified polymerase chain reaction (PCR) assay. had significant effects all plaque; physical properties AgNPs, as well specific sociodemographic clinical conditions patients, also associated bacterial growth inhibition Ag particles ( p < 0.05 ). PCR confirmed bacteria caries, such S. mutans sobrinus strains, principally. exhibited great potential used therapy control prevention